Blood flow and Disease

We study the way diseases change the viscoelastic properties of blood cells and how these changes affect the flow properties of blood.


Geislinger, T. M., and Franke, T. (2014) Hydrodynamic lift of vesicles and red blood cells in flow — from Fåhræus & Lindqvist to microfluidic cell sorting. Advances in Colloid and Interface Science, 208, pp. 161-176. (doi:10.1016/j.cis.2014.03.002)

Geislinger, T.M., and Franke, T. (2014) Filtern war gestern: Sortierung von zirkulierenden Tumorzellen in Lab-on-a-Chip Systemen. GIT Labor-Fachzeitschrift, 4, pp. 50-52.

Geislinger, T. M., Chan, S., Moll, K., Wixforth, A., Wahlgren, M., and Franke, T. (2014) Label-free microfluidic enrichment of ring-stage Plasmodium falciparum-infected red blood cells using non-inertial hydrodynamic lift. Malaria Journal, 13(1), p. 375. (doi:10.1186/1475-2875-13-375)

Geislinger, T. M., and Franke, T. (2013) Sorting of circulating tumor cells (MV3-melanoma) and red blood cells using non-inertial lift. Biomicrofluidics, 7(4), 044120. (doi:10.1063/1.4818907)

Geislinger, T.M., Eggart, B., Braunmüller, S., Schmid, L., and Franke, T. (2012) Separation of blood cells using hydrodynamic lift. Applied Physics Letters, 100(18), p. 183701. (doi:10.1063/1.4709614)


Hydrodynamic deformation

Braunmüller, S., Schmid, L., Sackmann, E., and Franke, T. (2012) Hydrodynamic deformation reveals two coupled modes/time scales of red blood cell relaxation. Soft Matter, 8(44), p. 11240. (doi:10.1039/C2SM26513C)

Braunmüller, S., Schmid, L., and Franke, T. (2011) Dynamics of red blood cells and vesicles in microchannels of oscillating width. Journal of Physics: Condensed Matter, 23(18), p. 184116. (doi:10.1088/0953-8984/23/18/184116)

Franke, T., Hoppe, R. H. W., Linsenmann, C., Schmid, L., Willbold, C., and Wixforth, A. (2011) Numerical simulation of the motion of red blood cells and vesicles in microfluidic flows. Computing and Visualization in Science, 14(4), pp. 167-180. (doi:10.1007/s00791-012-0172-1)



Forsyth, A. M., Braunmüller, S., Wan, J., Franke, T., and Stone, H. A. (2012) The effects of membrane cholesterol and simvastatin on red blood cell deformability and ATP release. Microvascular Research, 83(3), pp. 347-351. (doi:10.1016/j.mvr.2012.02.004)#

Franke, T., Braunmüller, S., Schmid, L., Wixforth, A., and Weitz, D. A. (2010) Surface acoustic wave actuated cell sorting (SAWACS). Lab on a Chip, 10(6), pp. 789-794. (doi:10.1039/B915522H)